IGF-1 LR3 is a synthetic, modified version of insulin-like growth factor 1, built as an 83-amino-acid chain with an extra section added to one end and a single swapped building block. It is best known in research for how it activates the IGF-1 receptor, and what sets it apart is that it largely sidesteps the binding proteins that normally hold IGF-1 in check.
It rests on an established research base, including early work characterizing how this kind of analog behaves with its binding proteins (Tomas et al., 1992, Biochemical Journal). That is why it often turns up as a reference compound in growth-factor signaling studies.
Research Applications
- IGF-1 receptor signaling research
- PI3K and Akt pathway studies
- Reduced binding-protein interaction models
- Growth-factor analog research
Supplied as a lyophilized powder for stability.
See also: HGH 176-191 5 mg, Sermorelin 5 mg, and AOD-9604 5 mg.
$21
IGF-1 LR3 Structure
Peptide Class: Synthetic 83-amino-acid IGF-1 analog; IGF-1-receptor agonist research peptide
Structural Modification: 13-amino-acid N-terminal extension (MFPAMPLLSLFVN) + Arg³ substitution
Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular Weight: ~9111 g/mol
CAS Number: 946870-92-4
PubChem CID: 168009904
Synonyms: Long R3 IGF-1, LR3 IGF-1
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