Retatrutide

Retatrutide is a synthetic peptide built from 39 amino acids. It is best known in research as a triple agonist, a single molecule designed to act on three receptors at once (GIP, GLP-1, and glucagon), which is what sets it apart from peptides that target just one.

It also has a growing research base, with work looking at how engaging these three pathways together shapes metabolic and insulin signaling (Coskun et al., 2022, Cell Metabolism). That is why it draws so much interest as a study compound in metabolic models.

Research Applications

• Incretin-pathway receptor research
• Insulin-signaling crosstalk studies
• Energy-metabolism research models
• Multi-receptor agonist studies

Supplied as a lyophilized powder for stability.

See also: Tirzepatide, Semaglutide, and Mazdutide 10 mg.

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Retatrutide Structure

Peptide Class: Synthetic triagonist research peptide (GIP/GLP-1/glucagon receptor)
Residues: 39 amino acids
Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight: ~4731 g/mol
CAS Number: 2381089-83-2
Research Code: LY3437943

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