SS-31

SS-31 (also called Elamipretide) is a small synthetic peptide made of four amino acids, built to home in on the inner membrane of the mitochondria, the cell’s energy centers. It is best known in research for the way it latches onto a lipid called cardiolipin, which is what makes it stand out as a mitochondria-focused study tool.

It also sits on a solid research foundation, with work exploring how it interacts with mitochondrial function and energy pathways (Birk et al., 2013, JASN). That is why it turns up often in cellular energy and longevity studies.

Research Applications

• Mitochondrial energy research
• Cardiolipin-binding studies
• Cellular bioenergetics models
• Longevity and aging research

Supplied as a lyophilized powder for stability.

See also: MOTS-c, NAD⁺, and Glutathione.

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SS-31 Structure

Peptide Class: Mitochondria-targeted aromatic-cationic tetrapeptide
Amino Acid Sequence: D-Arg-Dmt-Lys-Phe-NH₂
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: ~639.8 g/mol
CAS Number: 736992-21-5
PubChem CID: 11764719
Synonyms: Elamipretide, MTP-131, Bendavia

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