Melanotan 1 is a lab-made peptide built from 13 amino acids, designed as a close analog of the natural alpha-MSH hormone. It is best known in research for its activity at the melanocortin-1 receptor (MC1R), and its straight, linear chain is what marks it out among MSH analogs.
It also sits on a solid research base, with work exploring how it binds and signals at melanocortin receptors (Sawyer et al., 1980). This is why it often serves as a reference compound in melanocyte and receptor studies.
Research Applications
- MC1R receptor pharmacology research
- Melanocyte-signaling studies
- Alpha-MSH analog structure research
- Melanocortin receptor-binding work
Supplied as a lyophilized powder for stability.
See also: Melanotan 2, PT-141 10 mg, and GHK-Cu.
$21
Melanotan-1 Structure
Peptide Class: Synthetic linear alpha-MSH analog research peptide (melanocortin-receptor agonist)
Sequence: Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val
Residue Count: 13 amino acids (linear)
Key Structural Features: Nle4 substitution, D-Phe7 substitution
Molecular Formula: C₇₈H₁₁₁N₂₁O₁₉
Molecular Weight: ~1646.8 g/mol
CAS Number: 75921-69-6
Research Codes: NDP-MSH, NDP-alpha-MSH, afamelanotide
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