TB500 Fragment (17-23)

TB500 Fragment (17-23) is a short synthetic peptide, just seven amino acids long, that copies the core actin-binding stretch of the larger thymosin beta-4 protein. It is best known in research for this central LKKTETQ motif, which makes it a handy stand-in for studying how the full peptide grips actin.

It also draws on a solid research base built around thymosin beta-4, with published lab work exploring its activity (Sosne et al., 2003, FASEB Journal). That is why this defined fragment is a useful reference point for structure-activity work.

Research Applications

• Actin-binding and cytoskeleton research
• Structure-activity relationship studies
• Thymosin beta-4 fragment models
• Cellular-process laboratory research

Supplied as a lyophilized powder for stability.

See also: TB-500 10 mg, BPC-157, and KPV.

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TB500 Fragment (17-23) Structure

Peptide Class: Synthetic thymosin beta-4 active-site heptapeptide
Amino Acid Sequence: Leu-Lys-Lys-Thr-Glu-Thr-Gln
Sequence (single-letter): LKKTETQ
Corresponding Tβ4 Residues: 17-23
Molecular Formula: C₃₆H₆₆N₁₀O₁₃
Molecular Weight: ~847 g/mol
CAS Number: 476014-70-7
Alternative Designations: Thymosin beta-4 fragment (17-23), Tβ4 (17-23), Fequesetide

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